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Magnetic Bead-Immobilized Mammalian Cells are Effective Targets to Enrich Ligand-displaying Yeast

Yeast surface display empowers selection of protein binding ligands, typically using recombinant soluble antigens. However, ectodomain fragments of transmembrane targets may fail to recapitulate their true, membrane-bound form. Direct selections against adhered mammalian cells empower enrichment of...

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書目詳細資料
發表在:ACS Comb Sci
Main Authors: Lown, Patrick S., Hackel, Benjamin J.
格式: Artigo
語言:Inglês
出版: 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263704/
https://ncbi.nlm.nih.gov/pubmed/32283920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.0c00036
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