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Geometry and expression enhance enrichment of functional yeast-displayed ligands via cell panning

Yeast surface display has proven to be an effective tool in the discovery and evolution of ligands with new or improved binding activity. Selections for binding activity are generally carried out using immobilized or fluorescently labeled soluble domains of target molecules such as recombinant ectod...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Stern, Lawrence A., Schrack, Ian A., Johnson, Sadie M., Deshpande, Aakash, Bennett, Nathaniel R., Harasymiw, Lauren A., Gardner, Melissa K., Hackel, Benjamin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036992/
https://ncbi.nlm.nih.gov/pubmed/27144954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26001
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