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Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276

Yeast surface display is a proven tool for the selection and evolution of ligands with novel binding activity. Selections from yeast surface display libraries against transmembrane targets are generally carried out using recombinant soluble extracellular domains. Unfortunately, these molecules may n...

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Detalhes bibliográficos
Publicado no:ACS Comb Sci
Main Authors: Stern, Lawrence A., Lown, Patrick S., Kobe, Alexandra C., Abou-Elkacem, Lotfi, Willmann, Juergen K., Hackel, Benjamin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411437/
https://ncbi.nlm.nih.gov/pubmed/30620189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.8b00156
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