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Genetic dissociation of morphine analgesia from hyperalgesia
Morphine is the prototypic mu opioid, producing its analgesic actions through traditional 7 transmembrane domain (7TM) G-protein coupled receptors generated by the mu opioid receptor gene (Oprm1). However, the Oprm1 gene undergoes extensive alternative splicing to yield three structurally distinct s...
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| Veröffentlicht in: | Psychopharmacology (Berl) |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520541/ https://ncbi.nlm.nih.gov/pubmed/28343361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4600-2 |
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