A carregar...
Structure of the PRC2 complex and application to drug discovery
The polycomb repressive complexes 2 (PRC2) complex catalyzes tri-methylation of histone H3 lysine 27 (H3K27), a repressive chromatin marker associated with gene silencing. Overexpression and mutations of PRC2 are found in a wide variety of cancers, making the catalytic activity of PRC2 an important...
Na minha lista:
| Publicado no: | Acta Pharmacol Sin |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5519257/ https://ncbi.nlm.nih.gov/pubmed/28414199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.7 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|