Structure of the PRC2 complex and application to drug discovery

The polycomb repressive complexes 2 (PRC2) complex catalyzes tri-methylation of histone H3 lysine 27 (H3K27), a repressive chromatin marker associated with gene silencing. Overexpression and mutations of PRC2 are found in a wide variety of cancers, making the catalytic activity of PRC2 an important...

全面介紹

Na minha lista:
書目詳細資料
發表在:Acta Pharmacol Sin
Main Authors: Shi, Yi, Wang, Xiao-xi, Zhuang, You-wen, Jiang, Yi, Melcher, Karsten, Xu, H Eric
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519257/
https://ncbi.nlm.nih.gov/pubmed/28414199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.7
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍