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Androgen receptor: structure, role in prostate cancer and drug discovery

Androgens and androgen receptors (AR) play a pivotal role in expression of the male phenotype. Several diseases, such as androgen insensitivity syndrome (AIS) and prostate cancer, are associated with alterations in AR functions. Indeed, androgen blockade by drugs that prevent the production of andro...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Tan, MH Eileen, Li, Jun, Xu, H Eric, Melcher, Karsten, Yong, Eu-leong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571323/
https://ncbi.nlm.nih.gov/pubmed/24909511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.18
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