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Androgen receptor: structure, role in prostate cancer and drug discovery

Androgens and androgen receptors (AR) play a pivotal role in expression of the male phenotype. Several diseases, such as androgen insensitivity syndrome (AIS) and prostate cancer, are associated with alterations in AR functions. Indeed, androgen blockade by drugs that prevent the production of andro...

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Detalles Bibliográficos
Publicado en:Acta Pharmacol Sin
Main Authors: Tan, MH Eileen, Li, Jun, Xu, H Eric, Melcher, Karsten, Yong, Eu-leong
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571323/
https://ncbi.nlm.nih.gov/pubmed/24909511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.18
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