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Ion channels gated by acetylcholine and serotonin: structures, biology, and drug discovery
The nicotinic acetylcholine receptors (nAChRs) and the 5-HT(3) receptors (5-HT(3)Rs) are cation-selective members of the pentameric ligand-gated ion channels (pLGICs), which are oligomeric protein assemblies that convert a chemical signal into an ion flux through postsynaptic membrane. They are crit...
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| Publicado no: | Acta Pharmacol Sin |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4564887/ https://ncbi.nlm.nih.gov/pubmed/26238288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.66 |
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