Ion channels gated by acetylcholine and serotonin: structures, biology, and drug discovery

The nicotinic acetylcholine receptors (nAChRs) and the 5-HT(3) receptors (5-HT(3)Rs) are cation-selective members of the pentameric ligand-gated ion channels (pLGICs), which are oligomeric protein assemblies that convert a chemical signal into an ion flux through postsynaptic membrane. They are crit...

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Podrobná bibliografie
Vydáno v:Acta Pharmacol Sin
Hlavní autoři: Wu, Zhong-shan, Cheng, Hao, Jiang, Yi, Melcher, Karsten, Xu, H Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564887/
https://ncbi.nlm.nih.gov/pubmed/26238288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.66
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