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Monoclonal iNKT cell mice reveal a role for both tissue of origin and the TCR in development of iNKT functional subsets
iNKT cell functional subsets are defined by key transcription factors and output of cytokines such as IL-4, IFNγ, IL-17, and IL-10. To examine how TCR specificity determines iNKT function, we used somatic cell nuclear transfer to generate three lines of mice, cloned from iNKT nuclei. Each line uses...
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| Izdano u: | J Immunol |
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| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5518629/ https://ncbi.nlm.nih.gov/pubmed/28576977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700214 |
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