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IAP antagonists enhance cytokine production from mouse and human iNKT cells

Inhibitor of apoptosis protein (IAP) antagonists are in clinical trials for a variety of cancers, and mouse models show synergism between IAP antagonists and anti–PD-1 immunotherapy. Although IAP antagonists affect the intrinsic signaling of tumor cells, their most pronounced effects are on immune c...

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Bibliografische gegevens
Gepubliceerd in:Cancer Immunol Res
Hoofdauteurs: Clancy-Thompson, Eleanor, Ali, Lestat, Bruck, Patrick T., Exley, Mark A., Blumberg, Richard S., Dranoff, Glenn, Dougan, Michael, Dougan, Stephanie K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754232/
https://ncbi.nlm.nih.gov/pubmed/29187357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-17-0490
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