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Regulation of innate and adaptive antitumor immunity by IAP antagonists
Inhibition of the T-cell co-inhibitory checkpoint receptors or their ligands CTLA-4, PD-1 and PD-L1 using monoclonal antibodies has proven to be highly effective against many cancers. Yet many cancers remain resistant to checkpoint blockade, and durable remissions occur in only a minority of patient...
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| Publicado no: | Immunotherapy |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Future Medicine Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462841/ https://ncbi.nlm.nih.gov/pubmed/29807457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt-2017-0185 |
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