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Mutant lac repressors with new specificities hint at rules for protein--DNA recognition.

Proteins which recognize specific sequences of DNA play a fundamental role in the regulation of protein synthesis in all organisms. A particular helix of the bacterial protein lac repressor recognizes the bases in the major groove of the lac operator. We show that the first two residues of this reco...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Lehming, N, Sartorius, J, Kisters-Woike, B, von Wilcken-Bergmann, B, Müller-Hill, B
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 1990
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551714/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2178920/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08153.x
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