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Recognition helices of lac and lambda repressor are oriented in opposite directions and recognize similar DNA sequences.

Exchanges in positions 1 and 2 of the putative recognition helix allow lac repressor to bind to ideal lac operator variants in which base pair 4 has been replaced. We show here that an Arg-22----Asn exchange in position 6 of the putative recognition helix of lac repressor abolishes lac repressor bin...

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Bibliographic Details
Main Authors: Lehming, N, Sartorius, J, Oehler, S, von Wilcken-Bergmann, B, Müller-Hill, B
Format: Artigo
Language:Inglês
Published: 1988
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC282330/
https://ncbi.nlm.nih.gov/pubmed/3186699
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