Recognition helices of lac and lambda repressor are oriented in opposite directions and recognize similar DNA sequences.

Exchanges in positions 1 and 2 of the putative recognition helix allow lac repressor to bind to ideal lac operator variants in which base pair 4 has been replaced. We show here that an Arg-22----Asn exchange in position 6 of the putative recognition helix of lac repressor abolishes lac repressor bin...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lehming, N, Sartorius, J, Oehler, S, von Wilcken-Bergmann, B, Müller-Hill, B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282330/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3186699/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.7947
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