Mutant lac repressors with new specificities hint at rules for protein--DNA recognition.

Proteins which recognize specific sequences of DNA play a fundamental role in the regulation of protein synthesis in all organisms. A particular helix of the bacterial protein lac repressor recognizes the bases in the major groove of the lac operator. We show that the first two residues of this reco...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Lehming, N, Sartorius, J, Kisters-Woike, B, von Wilcken-Bergmann, B, Müller-Hill, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2178920/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08153.x
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