lac repressor forms loops with linear DNA carrying two suitably spaced lac operators.

Tetrameric lac repressor may bind to two lac operators on one DNA fragment and induce the intervening DNA to form a loop. Electron microscopy, non-denaturing polyacrylamide gel electrophoresis, and DNase I protection experiments were used to demonstrate such DNA loops, where the distance between the...

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Bibliographic Details
Published in:EMBO J
Main Authors: Krämer, H, Niemöller, M, Amouyal, M, Revet, B, von Wilcken-Bergmann, B, Müller-Hill, B
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1987
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3301328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02390.x
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