lac repressor forms loops with linear DNA carrying two suitably spaced lac operators.

Tetrameric lac repressor may bind to two lac operators on one DNA fragment and induce the intervening DNA to form a loop. Electron microscopy, non-denaturing polyacrylamide gel electrophoresis, and DNase I protection experiments were used to demonstrate such DNA loops, where the distance between the...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Krämer, H, Niemöller, M, Amouyal, M, Revet, B, von Wilcken-Bergmann, B, Müller-Hill, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3301328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02390.x
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