RARα2 and PML-RAR similarities in the control of basal and retinoic acid induced myeloid maturation of acute myeloid leukemia cells

Treatment of acute promyelocytic leukemia (APL) with all-trans retinoic acid (ATRA) is the first example of targeted therapy. In fact, the oncogenic fusion-protein (PML-RAR) typical of this leukemia contains the retinoid-nuclear-receptor RARα. PML-RAR is responsible for the differentiation block of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gianni, Maurizio, Fratelli, Maddalena, Bolis, Marco, Kurosaki, Mami, Zanetti, Adriana, Paroni, Gabriela, Rambaldi, Alessandro, Borleri, Gianmaria, Rochette-Egly, Cecile, Terao, Mineko, Garattini, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514891/
https://ncbi.nlm.nih.gov/pubmed/27419624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10556
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados