S100A3 a partner protein regulating the stability/activity of RARα and PML-RARα in cellular models of breast/lung cancer and acute myeloid leukemia

All trans-retinoic acid (ATRA) is used in the treatment of acute promyelocytic leukemia (APL) and it is a promising agent also in solid tumors. The pharmacological activity of ATRA is mediated by the ligand-activated RAR and RXR transcription factors. In the present study, we define the basal and AT...

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Bibliografske podrobnosti
izdano v:Oncogene
Main Authors: Gianni, Maurizio, Terao, Mineko, Kurosaki, Mami, Paroni, Gabriela, Brunelli, Laura, Pastorelli, Roberta, Zanetti, Adriana, Lupi, Monica, Acquavita, Andrea, Bolis, Marco, Fratelli, Maddalena, Rochette-Egly, Cecile, Garattini, Enrico
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484772/
https://ncbi.nlm.nih.gov/pubmed/30532072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0599-z
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