Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression

Forty-two cell lines recapitulating mammary carcinoma heterogeneity were profiled for all-trans retinoic acid (ATRA) sensitivity. Luminal and ER(+) (estrogen-receptor-positive) cell lines are generally sensitive to ATRA, while refractoriness/low sensitivity is associated with a Basal phenotype and H...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:EMBO Mol Med
Κύριοι συγγραφείς: Centritto, Floriana, Paroni, Gabriela, Bolis, Marco, Garattini, Silvio Ken, Kurosaki, Mami, Barzago, Maria Monica, Zanetti, Adriana, Fisher, James Neil, Scott, Mark Francis, Pattini, Linda, Lupi, Monica, Ubezio, Paolo, Piccotti, Francesca, Zambelli, Alberto, Rizzo, Paola, Gianni', Maurizio, Fratelli, Maddalena, Terao, Mineko, Garattini, Enrico
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley & Sons, Ltd 2015
Θέματα:
Research Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520659/
https://ncbi.nlm.nih.gov/pubmed/25888236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404670
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