Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression

Forty-two cell lines recapitulating mammary carcinoma heterogeneity were profiled for all-trans retinoic acid (ATRA) sensitivity. Luminal and ER(+) (estrogen-receptor-positive) cell lines are generally sensitive to ATRA, while refractoriness/low sensitivity is associated with a Basal phenotype and H...

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Publicat a:EMBO Mol Med
Autors principals: Centritto, Floriana, Paroni, Gabriela, Bolis, Marco, Garattini, Silvio Ken, Kurosaki, Mami, Barzago, Maria Monica, Zanetti, Adriana, Fisher, James Neil, Scott, Mark Francis, Pattini, Linda, Lupi, Monica, Ubezio, Paolo, Piccotti, Francesca, Zambelli, Alberto, Rizzo, Paola, Gianni', Maurizio, Fratelli, Maddalena, Terao, Mineko, Garattini, Enrico
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520659/
https://ncbi.nlm.nih.gov/pubmed/25888236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404670
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