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All-trans-retinoic Acid Modulates the Plasticity and Inhibits the Motility of Breast Cancer Cells: ROLE OF NOTCH1 AND TRANSFORMING GROWTH FACTOR (TGFβ)
All-trans-retinoic acid (ATRA) is a natural compound proposed for the treatment/chemoprevention of breast cancer. Increasing evidence indicates that aberrant regulation of epithelial-to-mesenchymal transition (EMT) is a determinant of the cancer cell invasive and metastatic behavior. The effects of...
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發表在: | J Biol Chem |
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Main Authors: | , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
American Society for Biochemistry and Molecular Biology
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505019/ https://ncbi.nlm.nih.gov/pubmed/26018078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.638510 |
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