All-trans-retinoic Acid Modulates the Plasticity and Inhibits the Motility of Breast Cancer Cells: ROLE OF NOTCH1 AND TRANSFORMING GROWTH FACTOR (TGFβ)

All-trans-retinoic acid (ATRA) is a natural compound proposed for the treatment/chemoprevention of breast cancer. Increasing evidence indicates that aberrant regulation of epithelial-to-mesenchymal transition (EMT) is a determinant of the cancer cell invasive and metastatic behavior. The effects of...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Zanetti, Adriana, Affatato, Roberta, Centritto, Floriana, Fratelli, Maddalena, Kurosaki, Mami, Barzago, Maria Monica, Bolis, Marco, Terao, Mineko, Garattini, Enrico, Paroni, Gabriela
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505019/
https://ncbi.nlm.nih.gov/pubmed/26018078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.638510
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