Retinoic Acid Sensitivity of Triple-Negative Breast Cancer Cells Characterized by Constitutive Activation of the notch1 Pathway: The Role of Rarβ

SIMPLE SUMMARY: We provide experimental evidence that the rare subgroup of triple-negative breast cancer characterized by constitutive activation of the NOTCH1 signaling pathway is sensitive to the anti-tumor action of all-trans retinoic acid, the active metabolite of vitamin A. In this tumor contex...

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Publicat a:Cancers (Basel)
Autors principals: Paroni, Gabriela, Zanetti, Adriana, Barzago, Maria Monica, Kurosaki, Mami, Guarrera, Luca, Fratelli, Maddalena, Troiani, Martina, Ubezio, Paolo, Bolis, Marco, Vallerga, Arianna, Biancardi, Federica, Terao, Mineko, Garattini, Enrico
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650753/
https://ncbi.nlm.nih.gov/pubmed/33081033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12103027
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