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Protein homeostasis of a metastable subproteome associated with Alzheimer’s disease

Alzheimer’s disease is the most common cause of dementia. A hallmark of this disease is the presence of aberrant deposits containing by the Aβ peptide (amyloid plaques) and the tau protein (neurofibrillary tangles) in the brains of affected individuals. Increasing evidence suggests that the formatio...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Kundra, Rishika, Ciryam, Prajwal, Morimoto, Richard I., Dobson, Christopher M., Vendruscolo, Michele
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514703/
https://ncbi.nlm.nih.gov/pubmed/28652376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618417114
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