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Protein homeostasis of a metastable subproteome associated with Alzheimer’s disease

Alzheimer’s disease is the most common cause of dementia. A hallmark of this disease is the presence of aberrant deposits containing by the Aβ peptide (amyloid plaques) and the tau protein (neurofibrillary tangles) in the brains of affected individuals. Increasing evidence suggests that the formatio...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kundra, Rishika, Ciryam, Prajwal, Morimoto, Richard I., Dobson, Christopher M., Vendruscolo, Michele
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514703/
https://ncbi.nlm.nih.gov/pubmed/28652376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618417114
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