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Protein homeostasis of a metastable subproteome associated with Alzheimer’s disease

Alzheimer’s disease is the most common cause of dementia. A hallmark of this disease is the presence of aberrant deposits containing by the Aβ peptide (amyloid plaques) and the tau protein (neurofibrillary tangles) in the brains of affected individuals. Increasing evidence suggests that the formatio...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kundra, Rishika, Ciryam, Prajwal, Morimoto, Richard I., Dobson, Christopher M., Vendruscolo, Michele
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514703/
https://ncbi.nlm.nih.gov/pubmed/28652376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618417114
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