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Supersaturation is a major driving force for protein aggregation in neurodegenerative diseases
The solubility of proteins is an essential requirement for their function. Yet these ubiquitous molecules can undergo aggregation when the protein homeostasis system becomes impaired. Here we ask which is the driving force for protein aggregation in the cellular environment. Emerging evidence sugges...
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| Wydane w: | Trends Pharmacol Sci |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4643722/ https://ncbi.nlm.nih.gov/pubmed/25636813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2014.12.004 |
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