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A transcriptional signature of Alzheimer’s disease is associated with a metastable subproteome at risk for aggregation
It is well-established that widespread transcriptional changes accompany the onset and progression of Alzheimer’s disease. Because of the multifactorial nature of this neurodegenerative disorder and its complex relationship with aging, however, it remains unclear whether such changes are the result...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4855616/ https://ncbi.nlm.nih.gov/pubmed/27071083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516604113 |
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