A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells

Approximately 70% of breast cancer cells express oestrogen receptor alpha (ERα). Previous studies have shown that the Brefeldin A-inhibited guanine nucleotide-exchange protein 3–prohibitin 2 (BIG3-PHB2) complex has a crucial role in these cells. However, it remains unclear how BIG3 regulates the sup...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Yoshimaru, Tetsuro, Ono, Masaya, Bando, Yoshimi, Chen, Yi-An, Mizuguchi, Kenji, Shima, Hiroshi, Komatsu, Masato, Imoto, Issei, Izumi, Keisuke, Honda, Junko, Miyoshi, Yasuo, Sasa, Mitsunori, Katagiri, Toyomasa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512694/
https://ncbi.nlm.nih.gov/pubmed/28555617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15427
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