Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (BIG3) is predicted to interact with its partner through an ARM-type α-helical structure

per Chen, Yi-An, Murakami, Yoichi, Ahmad, Shandar, Yoshimaru, Tetsuro, Katagiri, Toyomasa, Mizuguchi, Kenji
Publicat 2014

Therapeutic advances in BIG3-PHB2 inhibition targeting the crosstalk between estrogen and growth factors in breast cancer

per Yoshimaru, Tetsuro, Komatsu, Masato, Miyoshi, Yasuo, Honda, Junko, Sasa, Mitsunori, Katagiri, Toyomasa
Publicat a Cancer Sci (2015)

Early Growth Response 4 Is Involved in Cell Proliferation of Small Cell Lung Cancer through Transcriptional Activation of Its Downstream Genes

per Matsuo, Taisuke, Dat, Le Tan, Komatsu, Masato, Yoshimaru, Tetsuro, Daizumoto, Kei, Sone, Saburo, Nishioka, Yasuhiko, Katagiri, Toyomasa
Publicat a PLoS One (2014)

Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions

per Yoshimaru, Tetsuro, Komatsu, Masato, Tashiro, Etsu, Imoto, Masaya, Osada, Hiroyuki, Miyoshi, Yasuo, Honda, Junko, Sasa, Mitsunori, Katagiri, Toyomasa
Publicat a Sci Rep (2014)

BIG3 Inhibits the Estrogen-Dependent Nuclear Translocation of PHB2 via Multiple Karyopherin-Alpha Proteins in Breast Cancer Cells

per Kim, Nam-Hee, Yoshimaru, Tetsuro, Chen, Yi-An, Matsuo, Taisuke, Komatsu, Masato, Miyoshi, Yasuo, Tanaka, Eiji, Sasa, Mitsunori, Mizuguchi, Kenji, Katagiri, Toyomasa
Publicat a PLoS One (2015)

Stapled BIG3 helical peptide ERAP potentiates anti-tumour activity for breast cancer therapeutics

per Yoshimaru, Tetsuro, Aihara, Keisuke, Komatsu, Masato, Matsushita, Yosuke, Okazaki, Yasumasa, Toyokuni, Shinya, Honda, Junko, Sasa, Mitsunori, Miyoshi, Yasuo, Otaka, Akira, Katagiri, Toyomasa
Publicat a Sci Rep (2017)

Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin‐containing protein inhibitor

per Shikata, Yuki, Yoshimaru, Tetsuro, Komatsu, Masato, Katoh, Hiroto, Sato, Reiko, Kanagaki, Shuhei, Okazaki, Yasumasa, Toyokuni, Shinya, Tashiro, Etsu, Ishikawa, Shumpei, Katagiri, Toyomasa, Imoto, Masaya
Publicat a Cancer Sci (2017)

A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells

per Yoshimaru, Tetsuro, Ono, Masaya, Bando, Yoshimi, Chen, Yi-An, Mizuguchi, Kenji, Shima, Hiroshi, Komatsu, Masato, Imoto, Issei, Izumi, Keisuke, Honda, Junko, Miyoshi, Yasuo, Sasa, Mitsunori, Katagiri, Toyomasa
Publicat a Nat Commun (2017)

Targeting BIG3–PHB2 interaction to overcome tamoxifen resistance in breast cancer cells

per Yoshimaru, Tetsuro, Komatsu, Masato, Matsuo, Taisuke, Chen, Yi-An, Murakami, Yoichi, Mizuguchi, Kenji, Mizohata, Eiichi, Inoue, Tsuyoshi, Akiyama, Miki, Yamaguchi, Rui, Imoto, Seiya, Miyano, Satoru, Miyoshi, Yasuo, Sasa, Mitsunori, Nakamura, Yusuke, Katagiri, Toyomasa
Publicat 2013