Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (BIG3) is predicted to interact with its partner through an ARM-type α-helical structure

BACKGROUND: Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (BIG3) has been identified recently as a novel regulator of estrogen signalling in breast cancer cells. Despite being a potential target for new breast cancer treatment, its amino acid sequence suggests no association with any w...

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Bibliographic Details
Main Authors: Chen, Yi-An, Murakami, Yoichi, Ahmad, Shandar, Yoshimaru, Tetsuro, Katagiri, Toyomasa, Mizuguchi, Kenji
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096751/
https://ncbi.nlm.nih.gov/pubmed/24997568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-435
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