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Stapled BIG3 helical peptide ERAP potentiates anti-tumour activity for breast cancer therapeutics
Estradiol (E2) and the oestrogen receptor-alpha (ERα) signalling pathway play pivotal roles in the proliferative activity of breast cancer cells. Recent findings show that the brefeldin A-inhibited guanine nucleotide-exchange protein 3-prohibitin 2 (BIG3-PHB2) complex plays a crucial role in E2/ERα...
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| Published in: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431889/ https://ncbi.nlm.nih.gov/pubmed/28500289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01951-6 |
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