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HIV-1 enhances mTORC1 activity and repositions lysosomes to the periphery by co-opting Rag GTPases
HIV-1 co-opts several host machinery to generate a permissive environment for viral replication and transmission. In this work we reveal how HIV-1 impacts the host translation and intracellular vesicular trafficking machineries for protein synthesis and to impede the physiological late endosome/lyso...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5511174/ https://ncbi.nlm.nih.gov/pubmed/28710431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05410-0 |
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