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An anti‐nicotinic cognitive challenge model using mecamylamine in comparison with the anti‐muscarinic cognitive challenge using scopolamine

AIMS: The muscarinic acetylcholine receptor antagonist scopolamine is often used for proof‐of‐pharmacology studies with pro‐cognitive compounds. From a pharmacological point of view, it would seem more rational to use a nicotinic rather than a muscarinic anticholinergic challenge to prove pharmacolo...

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Dades bibliogràfiques
Publicat a:Br J Clin Pharmacol
Autors principals: Baakman, Anne Catrien, Alvarez‐Jimenez, Ricardo, Rissmann, Robert, Klaassen, Erica S., Stevens, Jasper, Goulooze, Sebastiaan C., den Burger, Jeroen C. G., Swart, Eleonora L., van Gerven, Joop M. A., Groeneveld, Geert Jan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510063/
https://ncbi.nlm.nih.gov/pubmed/28217868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13268
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