Biomarkers for the effects of cannabis and THC in healthy volunteers

Por Zuurman, Lineke, Ippel, Annelies E, Moin, Eduard, van Gerven, Joop M A
Publicado em 2009

The Role of the Noradrenergic System in the Exploration–Exploitation Trade-Off: A Psychopharmacological Study

Por Jepma, Marieke, te Beek, Erik T., Wagenmakers, Eric-Jan, van Gerven, Joop M.A., Nieuwenhuis, Sander
Publicado em 2010

Functional biomarkers for the acute effects of alcohol on the central nervous system in healthy volunteers

Por Zoethout, Remco W M, Delgado, Wilson L, Ippel, Annelies E, Dahan, Albert, van Gerven, Joop M A
Publicado em 2011

Pharmacokinetic/pharmaco–dynamic modelling and simulation of the effects of different cannabinoid receptor type 1 antagonists on Δ(9)‐tetrahydrocannabinol challenge tests

Por Guan, Zheng, Klumpers, Linda E., Oyetayo, Olubukayo‐Opeyemi, Heuberger, Jules, van Gerven, Joop M. A., Stevens, Jasper
Publicado no Br J Clin Pharmacol (2016)

Acute effects of MDMA (3,4-methylenedioxymethamphetamine) on EEG oscillations: alone and in combination with ethanol or THC (delta-9-tetrahydrocannabinol)

Por Lansbergen, Marieke M., Dumont, Glenn J. H., van Gerven, Joop M. A., Buitelaar, Jan K., Verkes, Robbert-Jan
Publicado em 2010

Lessons Learned and Potentials for Improvement in CNS Drug Development: ISCTM Section on Designing the Right Series of Experiments

Por Szabo, Steven T., Kinon, Bruce J., Brannan, Stephen K., Krystal, Andrew K., van Gerven, Joop M. A., Mahableshwarkar, Atul, Sachs, Gary S.
Publicado no Innov Clin Neurosci (2015)

Central nervous system effects of moxonidine experimental sustained release formulation in patients with mild to moderate essential hypertension

Por Kemme, Michiel J B, Post, Jeroen P vd, Schoemaker, Rik C, Straub, Matthias, Cohen, Adam F, van Gerven, Joop M A
Publicado em 2003

Central nervous system effects of alcohol at a pseudo-steady-state concentration using alcohol clamping in healthy volunteers

Por Zoethout, Remco W M, Schoemaker, Rik C, Zuurman, Lineke, van Pelt, Hans, Dahan, Albert, Cohen, Adam F, van Gerven, Joop M A
Publicado em 2009

Model‐based exposure‐response analysis to quantify age related differences in the response to scopolamine in healthy subjects

Por Alvarez‐Jimenez, Ricardo, Groeneveld, Geert Jan, van Gerven, Joop M. A., Goulooze, Sebastiaan C., Baakman, Anne Catrien, Hay, Justin L., Stevens, Jasper
Publicado no Br J Clin Pharmacol (2016)

Diminished Posterior Precuneus Connectivity with the Default Mode Network Differentiates Normal Aging from Alzheimer's Disease

Por Klaassens, Bernadet L., van Gerven, Joop M. A., van der Grond, Jeroen, de Vos, Frank, Möller, Christiane, Rombouts, Serge A. R. B.
Publicado no Front Aging Neurosci (2017)

A study of the effects of long-term use on individual sensitivity to temazepam and lorazepam in a clinical population

Por van Steveninck, Alfred L., Wallnöfer, Andreas E., Schoemaker, Rik C., Pieters, Monique S. M., Danhof, Meindert, van Gerven, Joop M. A., Cohen, Adam F.
Publicado em 1997

Pharmacokinetic–pharmacodynamic relationships of central nervous system effects of scopolamine in healthy subjects

Por Liem-Moolenaar, Marieke, de Boer, Peter, Timmers, Maarten, Schoemaker, Rik C, van Hasselt, J G Coen, Schmidt, Stephan, van Gerven, Joop M A
Publicado em 2011

Central nervous system effects of the interaction between risperidone (single dose) and the 5-HT(6) antagonist SB742457 (repeated doses) in healthy men

Por Liem-Moolenaar, Marieke, Rad, Mandana, Zamuner, Stefano, Cohen, Adam F, Lemme, Francesca, Franson, Kari L, van Gerven, Joop M A, Pich, Emilio Merlo
Publicado em 2011

Delta-9-Tetrahydrocannabinol-Induced Dopamine Release as a Function of Psychosis Risk: (18)F-Fallypride Positron Emission Tomography Study

Por Kuepper, Rebecca, Ceccarini, Jenny, Lataster, Johan, van Os, Jim, van Kroonenburgh, Marinus, van Gerven, Joop M. A., Marcelis, Machteld, Van Laere, Koen, Henquet, Cécile
Publicado em 2013

Time related effects on functional brain connectivity after serotonergic and cholinergic neuromodulation

Por Klaassens, Bernadet L., Rombouts, Serge A.R.B., Winkler, Anderson M., van Gorsel, Helene C., van der Grond, Jeroen, van Gerven, Joop M.A.
Publicado no Hum Brain Mapp (2016)

Peripheral selectivity of the novel cannabinoid receptor antagonist TM38837 in healthy subjects

Por Klumpers, Linda E, Fridberg, Marianne, de Kam, Marieke L, Little, Paul B, Jensen, Niels Ole, Kleinloog, Hendrik D, Elling, Christian E, van Gerven, Joop M A
Publicado em 2013

Pharmacokinetics and pharmacodynamics of a new highly concentrated intranasal midazolam formulation for conscious sedation

Por Schrier, Lenneke, Zuiker, Rob, Merkus, Frans W. H. M., Klaassen, Erica S., Guan, Zheng, Tuk, Bert, van Gerven, Joop M. A., van der Geest, Ronald, Groeneveld, Geert Jan
Publicado no Br J Clin Pharmacol (2016)

Surinabant, a selective cannabinoid receptor type 1 antagonist, inhibits Δ(9)-tetrahydrocannabinol-induced central nervous system and heart rate effects in humans

Por Klumpers, Linda E, Roy, Christine, Ferron, Geraldine, Turpault, Sandrine, Poitiers, Franck, Pinquier, Jean-Louis, van Hasselt, Johan G C, Zuurman, Lineke, Erwich, Frank A S, van Gerven, Joop M A
Publicado em 2013

A comparative study of two methods for attaining constant alcohol levels

Por Zoethout, Remco W M, van Gerven, Joop M A, Dumont, Glenn J H, Paltansing, Sunita, van Burgel, Nathalie D, van der Linden, Monique, Dahan, Albert, Cohen, Adam F, Schoemaker, Rik C
Publicado em 2008

Novel Δ(9)-tetrahydrocannabinol formulation Namisol® has beneficial pharmacokinetics and promising pharmacodynamic effects

Por Klumpers, Linda E, Beumer, Tim L, van Hasselt, Johan G C, Lipplaa, Astrid, Karger, Lennard B, Kleinloog, H Daniël, Freijer, Jan I, de Kam, Marieke L, van Gerven, Joop M A
Publicado em 2012