Reversal of mecamylamine‐induced effects in healthy subjects by nicotine receptor agonists: Cognitive and (electro) physiological responses

AIMS: Establishing a pharmacological challenge model could yield an important tool to understand the complex role of the nicotinic cholinergic system in cognition and to develop novel compounds acting on the nicotinic acetylcholine receptor. METHODS: This randomized, double‐blind, double‐dummy, plac...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Alvarez‐Jimenez, Ricardo, Hart, Ellen P., Prins, Samantha, de Kam, Marieke, van Gerven, Joop M.A., Cohen, Adam F., Groeneveld, Geert Jan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Pharmacodynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903244/
https://ncbi.nlm.nih.gov/pubmed/29319910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13507
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