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Reversal of mecamylamine‐induced effects in healthy subjects by nicotine receptor agonists: Cognitive and (electro) physiological responses

AIMS: Establishing a pharmacological challenge model could yield an important tool to understand the complex role of the nicotinic cholinergic system in cognition and to develop novel compounds acting on the nicotinic acetylcholine receptor. METHODS: This randomized, double‐blind, double‐dummy, plac...

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Publicado en:Br J Clin Pharmacol
Main Authors: Alvarez‐Jimenez, Ricardo, Hart, Ellen P., Prins, Samantha, de Kam, Marieke, van Gerven, Joop M.A., Cohen, Adam F., Groeneveld, Geert Jan
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903244/
https://ncbi.nlm.nih.gov/pubmed/29319910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13507
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