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Reversal of mecamylamine‐induced effects in healthy subjects by nicotine receptor agonists: Cognitive and (electro) physiological responses

AIMS: Establishing a pharmacological challenge model could yield an important tool to understand the complex role of the nicotinic cholinergic system in cognition and to develop novel compounds acting on the nicotinic acetylcholine receptor. METHODS: This randomized, double‐blind, double‐dummy, plac...

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Vydáno v:Br J Clin Pharmacol
Hlavní autoři: Alvarez‐Jimenez, Ricardo, Hart, Ellen P., Prins, Samantha, de Kam, Marieke, van Gerven, Joop M.A., Cohen, Adam F., Groeneveld, Geert Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903244/
https://ncbi.nlm.nih.gov/pubmed/29319910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13507
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