Reversal of mecamylamine‐induced effects in healthy subjects by nicotine receptor agonists: Cognitive and (electro) physiological responses

AIMS: Establishing a pharmacological challenge model could yield an important tool to understand the complex role of the nicotinic cholinergic system in cognition and to develop novel compounds acting on the nicotinic acetylcholine receptor. METHODS: This randomized, double‐blind, double‐dummy, plac...

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Publicat a:Br J Clin Pharmacol
Autors principals: Alvarez‐Jimenez, Ricardo, Hart, Ellen P., Prins, Samantha, de Kam, Marieke, van Gerven, Joop M.A., Cohen, Adam F., Groeneveld, Geert Jan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Pharmacodynamics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903244/
https://ncbi.nlm.nih.gov/pubmed/29319910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13507
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