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Aurora A, MCAK, and Kif18b promote Eg5-independent spindle formation
Inhibition of the microtubule (MT) motor protein Eg5 results in a mitotic arrest due to the formation of monopolar spindles, making Eg5 an attractive target for anti-cancer therapies. However, Eg5-independent pathways for bipolar spindle formation exist, which might promote resistance to treatment w...
Tallennettuna:
| Julkaisussa: | Chromosoma |
|---|---|
| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Springer Berlin Heidelberg
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5509784/ https://ncbi.nlm.nih.gov/pubmed/27354041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-016-0607-4 |
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