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Regulation of localization and activity of the microtubule depolymerase MCAK

Mitotic Centromere Associated Kinesin (MCAK) is a potent microtubule depolymerizing and catastrophe-inducing factor, which uses the energy of ATP hydrolysis to destabilize microtubule ends. MCAK is localized to inner centromeres, kinetochores and spindle poles of mitotic cells, and is also present i...

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Detalhes bibliográficos
Main Authors: Tanenbaum, Marvin E, Medema, René H, Akhmanova, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158623/
https://ncbi.nlm.nih.gov/pubmed/21866268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bioa.1.2.15807
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