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Regulation of localization and activity of the microtubule depolymerase MCAK

Mitotic Centromere Associated Kinesin (MCAK) is a potent microtubule depolymerizing and catastrophe-inducing factor, which uses the energy of ATP hydrolysis to destabilize microtubule ends. MCAK is localized to inner centromeres, kinetochores and spindle poles of mitotic cells, and is also present i...

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Autores principales: Tanenbaum, Marvin E, Medema, René H, Akhmanova, Anna
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158623/
https://ncbi.nlm.nih.gov/pubmed/21866268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bioa.1.2.15807
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