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Regulation of localization and activity of the microtubule depolymerase MCAK

Mitotic Centromere Associated Kinesin (MCAK) is a potent microtubule depolymerizing and catastrophe-inducing factor, which uses the energy of ATP hydrolysis to destabilize microtubule ends. MCAK is localized to inner centromeres, kinetochores and spindle poles of mitotic cells, and is also present i...

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Bibliografische gegevens
Hoofdauteurs: Tanenbaum, Marvin E, Medema, René H, Akhmanova, Anna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158623/
https://ncbi.nlm.nih.gov/pubmed/21866268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bioa.1.2.15807
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