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Aurora A Phosphorylates MCAK to Control Ran-dependent Spindle Bipolarity

During mitosis, mitotic centromere-associated kinesin (MCAK) localizes to chromatin/kinetochores, a cytoplasmic pool, and spindle poles. Its localization and activity in the chromatin region are regulated by Aurora B kinase; however, how the cytoplasmic- and pole-localized MCAK are regulated is curr...

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Autori principali: Zhang, Xin, Ems-McClung, Stephanie C., Walczak, Claire E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441684/
https://ncbi.nlm.nih.gov/pubmed/18434591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0198
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