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The far C-terminus of MCAK regulates its conformation and spindle pole focusing
To ensure proper spindle assembly, microtubule (MT) dynamics needs to be spatially regulated within the cell. The kinesin-13 MCAK is a potent MT depolymerase with a complex subcellular localization, yet how MCAK spatial regulation contributes to spindle assembly is not understood. Here we show that...
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| Vydáno v: | Mol Biol Cell |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Cell Biology
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850033/ https://ncbi.nlm.nih.gov/pubmed/26941326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-10-0699 |
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