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Nuclear envelope-associated dynein cooperates with Eg5 to drive prophase centrosome separation
Eg5 (kinesin-5) is a highly conserved microtubule motor protein, essential for centrosome separation and bipolar spindle assembly in human cells. Using an “in vitro” evolution approach, we generated human cancer cells that can grow in the complete absence of Eg5 activity. Characterization of these E...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656018/ https://ncbi.nlm.nih.gov/pubmed/23713137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.23841 |
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