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Nuclear envelope-associated dynein cooperates with Eg5 to drive prophase centrosome separation

Eg5 (kinesin-5) is a highly conserved microtubule motor protein, essential for centrosome separation and bipolar spindle assembly in human cells. Using an “in vitro” evolution approach, we generated human cancer cells that can grow in the complete absence of Eg5 activity. Characterization of these E...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: van Heesbeen, Roy G.H.P., Raaijmakers, Jonne A., Tanenbaum, Marvin E., Medema, René H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Landes Bioscience 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656018/
https://ncbi.nlm.nih.gov/pubmed/23713137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.23841
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