miR-33 regulates macrophage autophagy in atherosclerosis

OBJECTIVE: Defective autophagy in macrophages leads to pathologic processes that contribute to atherosclerosis, including impaired cholesterol metabolism and defective efferocytosis. Autophagy promotes the degradation of cytoplasmic components in lysosomes and plays a key role in the catabolism of s...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Ouimet, Mireille, Ediriweera, Hasini, Afonso, Milessa Silva, Ramkhelawon, Bhama, Singaravelu, Ragunath, Liao, Xianghai, Bandler, Rachel C, Rahman, Karishma, Fisher, Edward A, Rayner, Katey J, Pezacki, John P, Tabas, Ira, Moore, Kathryn J
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494696/
https://ncbi.nlm.nih.gov/pubmed/28428217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308916
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