Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

The lipid droplet (LD) is the major site of cholesterol storage in macrophage foam cells and is a potential therapeutic target for the treatment of atherosclerosis. Cholesterol, stored as cholesteryl esters (CEs), is liberated from this organelle and delivered to cholesterol acceptors. The current p...

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Hlavní autoři: Ouimet, Mireille, Franklin, Vivian, Mak, Esther, Liao, Xianghai, Tabas, Ira, Marcel, Yves L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257518/
https://ncbi.nlm.nih.gov/pubmed/21641547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.03.023
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