Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

In advanced atherosclerosis, macrophage apoptosis coupled with defective phagocytic clearance of the apoptotic cells (efferocytosis) promotes plaque necrosis, which precipitates acute atherothrombotic cardiovascular events. Oxidative and endoplasmic reticulum (ER) stress in macrophages are important...

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Detalhes bibliográficos
Main Authors: Liao, Xianghai, Sluimer, Judith C., Wang, Ying, Subramanian, Manikandan, Brown, Kristy, Pattison, J. Scott, Robbins, Jeffrey, Martinez, Jennifer, Tabas, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322248/
https://ncbi.nlm.nih.gov/pubmed/22445600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.01.022
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