Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

In advanced atherosclerosis, macrophage apoptosis coupled with defective phagocytic clearance of the apoptotic cells (efferocytosis) promotes plaque necrosis, which precipitates acute atherothrombotic cardiovascular events. Oxidative and endoplasmic reticulum (ER) stress in macrophages are important...

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Main Authors: Liao, Xianghai, Sluimer, Judith C., Wang, Ying, Subramanian, Manikandan, Brown, Kristy, Pattison, J. Scott, Robbins, Jeffrey, Martinez, Jennifer, Tabas, Ira
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322248/
https://ncbi.nlm.nih.gov/pubmed/22445600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.01.022
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