HIV-1 integrase crosslinked oligomers are active in vitro

The oligomeric state of active human immunodeficiency virus type 1 (HIV-1) integrase (IN) has not been clearly elucidated. We analyzed the activity of the different purified oligomeric forms of recombinant IN obtained after stabilization by platinum crosslinking. The crosslinked tetramer isolated by...

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Autors principals: Faure, Aurélie, Calmels, Christina, Desjobert, Cécile, Castroviejo, Michel, Caumont-Sarcos, Anne, Tarrago-Litvak, Laura, Litvak, Simon, Parissi, Vincent
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2005
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC549407/
https://ncbi.nlm.nih.gov/pubmed/15718297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki241
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