Chromosomal integration of LTR-flanked DNA in yeast expressing HIV-1 integrase: down regulation by RAD51

HIV-1 integrase (IN) is the key enzyme catalyzing the proviral DNA integration step. Although the enzyme catalyzes the integration step accurately in vitro, whether IN is sufficient for in vivo integration and how it interacts with the cellular machinery remains unclear. We set up a yeast cellular i...

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Main Authors: Desfarges, S., San Filippo, J., Fournier, M., Calmels, C., Caumont-Sarcos, A., Litvak, S., Sung, P., Parissi, V.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2006
Teme:
Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693895/
https://ncbi.nlm.nih.gov/pubmed/17090598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl843
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