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HIV-1 integrase crosslinked oligomers are active in vitro

The oligomeric state of active human immunodeficiency virus type 1 (HIV-1) integrase (IN) has not been clearly elucidated. We analyzed the activity of the different purified oligomeric forms of recombinant IN obtained after stabilization by platinum crosslinking. The crosslinked tetramer isolated by...

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Détails bibliographiques
Auteurs principaux: Faure, Aurélie, Calmels, Christina, Desjobert, Cécile, Castroviejo, Michel, Caumont-Sarcos, Anne, Tarrago-Litvak, Laura, Litvak, Simon, Parissi, Vincent
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2005
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC549407/
https://ncbi.nlm.nih.gov/pubmed/15718297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki241
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